首页>
外国专利>
HUMAN LEUKOCYTE ANTIGEN-G (HLA-G) MODIFIED CELLS AND METHODS
HUMAN LEUKOCYTE ANTIGEN-G (HLA-G) MODIFIED CELLS AND METHODS
展开▼
机译:人白细胞抗原-G(HLA-G)修饰的细胞和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Disclosed herein are genetically modified cells expressing HLA-G (e.g., cell surface HLA-G) persistently, and nucleic acid compositions useful for generating such genetically modified cells. Also disclosed are cell therapy methods that utilize genetically modified cells that express HLA-G persistently. The HLA-G genetic modifications described herein provide the cells with characteristics of reduced immunogenicity and/or improved immunosuppression, such that these cells have the promise of being universal or improved donor cells for transplants, cellular and tissue regeneration or reconstruction, and other therapies.
展开▼