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Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells
Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells
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机译:基于直接针对抗原呈递细胞的抗体靶向佐剂的新型疫苗佐剂
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摘要
Compositions and methods for enhancing an immune response with an adjuvant composition comprising: an anti-dendritic cell (DC)-specific antibody or fragment thereof conjugated to at least a portion of a TLR agonist; and a pharmaceutically acceptable carrier are disclosed herein. The conjugate and agonist are each comprised in an amount such that, in combination with the other, are effective to produce the immune response in a human or animal subject in need of immunostimulation.
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