AUTOMATED DETECTION, TRACKING AND ANALYSIS OF CELL MIGRATION IN A 3-D MATRIX SYSTEM

摘要

A data processing system receives an image of a matrix including a plurality of living cells. The data processing system automatically locates a cell among the plurality of living cells in the image by performing image processing on the image. In response to locating the cell, the data processing system records, in data storage, a position of the cell in the image. The data processing system may further automatically determine, based on the image, one or more selected metrics for the cell, such as one or more motility metrics, one or more frequency metrics and/or one or more morphology metrics. Based on the one or more metrics, the data processing system may further automatically determine a probability of success of a therapy on a patient employing a test substance and/or automatically select a treatment plan for recommendation.