METHOD FOR PRODUCING NOVEL NANO-BUBBLE POLY-LIPO-PLEX HAVING ANIONIC PROPERTY

摘要

The present invention mainly addresses the problem of providing a means for further improving the efficiency of the introduction of a nucleic acid and optionally a compound such as a protein or a medicinal agent into a cell.As the means for solving the problem, an anionic nano-bubble poly-lipo-plex is provided, which comprises a complex of an anionic polymer and a positively-charged polymer and an anionic liposome, wherein the liposome contains bubbles and the complex is cationic.