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BONE GRAFT AND SCAFFOLDING MATERIALS IMMOBILIZED WITH TYPE I COLLAGEN BINDING PEPTIDES
BONE GRAFT AND SCAFFOLDING MATERIALS IMMOBILIZED WITH TYPE I COLLAGEN BINDING PEPTIDES
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机译:固定有I型胶原结合肽的骨移植物和脚手架材料
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摘要
The present invention relates to a pharmaceutical composition comprising a bone graft material, a scaffold for tissue engineering applications and type I collagen Binding Peptides which have bone calcification-promoting peptides immobilized on the surface, and more particularly, to a bone graft material and a scaffold for tissue engineering applications (hereinafter, referred to as scaffold), which have peptides specifically binding with type I collagen immobilized on the surface, and pharmaceutical composition for recovering tissue regeneration containing type I collagen binding-inducing peptide. In the inventive bone graft material and scaffold for tissue engineering applications, the cells related to regeneration by collagen binding-inducing peptide adhered to the surface, promote an adhesion of type I collagen binding-inducing peptide (main ingredients of extracellular matrix) to increase differentiation rate into bone tissues, and promote a calcification which is last step of bone regeneration to maximize a tissue regeneration finally.
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