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USING HAPLOTYPES TO INFER ANCESTRAL ORIGINS FOR RECENTLY ADMIXED INDIVIDUALS

机译:使用单型来推断最近个体的祖先起源

摘要

Phased haplotype features are used to infer an individual's ancestry. Reference genomic data is obtained for individuals of known ancestral origin. Haplotype features are identified based on consecutive SNPs from each individual. Sample genomic data is obtained for an individual of unknown ancestral origin. The data is phased and divided into features analogous to the features in the reference data. An admixture estimator then performs an admixture estimation based on the observed feature values in the sample data and the reference data. The estimation indicates a contribution of each of the known populations to the genome of the sample individual.
机译:分阶段的单倍型特征可用于推断个人的血统。获得已知祖先个体的参考基因组数据。基于来自每个个体的连续SNP来鉴定单倍型特征。获得了祖先来源未知的个体的样本基因组数据。数据被分阶段并分为与参考数据中的特征相似的特征。然后,混合估计器基于样本数据和参考数据中观察到的特征值执行混合估计。该估计表明每个已知种群对样品个体基因组的贡献。

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