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FEAR OR ANXIETY MEASURING SYSTEM

机译:恐惧或焦虑测量系统

摘要

Provided is a method for screening drugs that control emotions (for example preventative or treatment drugs for psychiatric disorders), or aromas that have relaxing effects. A method for screening drugs that control emotions (for example preventative or treatment drugs for psychiatric disorders), or aromas, the method being characterised by comprising: (a) a step for administering a test substance to a test animal or exposing the test animal to the test substance; (b) a step for exposing the test animal to a substance that induces innate fear such as 2-methyl-2-thiazoline or 2, 5-dimethyl-2-thiazoline; (c) a step for measuring at least one value selected from the freezing time, body surface temperature, internal body temperature, and heart rate of the test animal; and (d) a step for selecting a test substance that alters the freezing time, that adjusts a reduction in body surface temperature, that adjusts a reduction in internal body temperature, or that that adjusts a reduction in the heart rate.
机译:提供了一种筛选用于控制情绪的药物(例如用于精神疾病的预防或治疗药物)或具有放松作用的香气的方法。一种用于筛选控制情绪的药物(例如用于精神疾病的预防或治疗药物)或香气的方法,该方法的特征在于包括:(a)向被测动物施用被测物质或将被测动物暴露于以下环境的步骤:测试物质; (b)使试验动物暴露于引起先天性恐惧的物质如2-甲基-2-噻唑啉或2,5-二甲基-2-噻唑啉的步骤; (c)测量至少一个选自试验动物的冻结时间,体表温度,体内温度和心率的值的步骤; (d)选择改变冻结时间,调节体表温度降低,调节体内温度降低或调节心率降低的测试物质的步骤。

著录项

  • 公开/公告号WO2014081017A1

    专利类型

  • 公开/公告日2014-05-30

    原文格式PDF

  • 申请/专利权人 OSAKA BIOSCIENCE INSTITUTE;

    申请/专利号WO2013JP81548

  • 发明设计人 KOBAYAKAWA KO;KOBAYAKAWA REIKO;

    申请日2013-11-22

  • 分类号G01N33/15;G01N33/50;

  • 国家 WO

  • 入库时间 2022-08-21 15:49:30

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