USE OF miRNA ANTAGONISTS FOR IMMUNE SYSTEM MODULATION, TREATMENT OF BACTERIAL INFECTIONS AND TREATMENT OF AIRWAYS DISEASES

摘要

Disclosed herein are immunostimulatory compositions comprising at least one agent capable of inhibiting the expression and/or activity of miR-328-3p, a precursor or variant thereof or a miRNA comprising a seed region comprising the sequence UGGCCCU. Also disclosed herein are uses of said compositions for, inter alia, treating bacterial infections, promoting bacterial clearance, treating airways diseases and treating immunodeficiency.