HIGHLY SELECTIVE ASYMMETRIC HYDROFORMYLATION OF (1S,4R) OR (1R,4S)-2-AZABICYCLO2.2.1HEPT-5-EN-3- ONE (+) OR (-)-LACTAM

摘要

Methods of producing the compounds of formula (22) and (23) or enantiomers thereof comprising hydroformylation of compounds of the formula (21) or their enantiomers: using Kelliphite as chiral ligand wherein R is -H or an amine-protecting group.