PANAXATRIOL SAPONINS ENTERIC PELLET, CAPSULE COMPRISING SAME AND METHOD FOR PREPARING SAME

摘要

Disclosed are a panaxatriol saponins enteric pellet and a method for preparing same, and a capsule comprising the enteric pellet. The enteric pellet comprises a core having a diameter of 20-24 mesh consisting of panaxatriol saponins and pharmaceutical necessities, and an enteric coating layer over the core, wherein the panaxatriol saponins, the pharmaceutical necessities and the enteric coating layer are in a weight ratio of 100:(165-208):(45-65). Preferred pharmaceutical necessities consist of microcrystalline cellulose, starch and polyvidone K30 in a weight ratio of (80-100):(80-100):(5-6), or consist of microcrystalline cellulose, micronized silica gel and polyvidone K30 in a weight ratio of 100:100:8. Preferred enteric pellet has the following components and weight ratio thereof of panaxatriol saponins : microcrystalline cellulose : starch : polyvidone K30 : enteric coating layer = 100:93:93:5.7:58.3, or panaxatriol saponins : microcrystalline cellulose : micronized silica gel : polyvidone K30 : enteric coating layer = 100:100:100:8:62. The enteric pellet is prepared by fluid-bed method or extrusion-spheronization method.