CIRCULATING BMEC AND RELATED CELLS AS BIOMARKERS OF CNS DISEASES ASSOCIATED WITH THE BLOOD-BRAIN-BARRIER DISORDERS

摘要

Described herein are processes, assays and methods for detecting damage to the blood-brain barrier by assaying the levels of any one or more of cBMEC, EPC and/or UCHL1. An increase in the levels of cBMEC, EPC and/or UCHL1 in a sample obtained from the subject is indicative of damage to the blood-brain barrier.