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NOVEL MYCOBACTERIUM TUBERCULOSIS TARGET AND USE THEREOF IN THE SCREENING OF ANTI-TUBERCULOSIS DRUGS

机译：新型结核分枝杆菌靶标及其在抗结核药物筛查中的应用

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摘要

The invention relates to a novel Mycobacterium tuberculosis target and to the use thereof in the screening of anti-tuberculosis drugs, more specifically a recombinant asparaginase of Mycobacterium tuberculosis, an inhibitor of this protein, and to a screening method for selecting said inhibitor. The invention also relates to a mutant strain of Mycobacterium tuberculosis.

机译：本发明涉及新型结核分枝杆菌靶标及其在抗结核药物，更具体地说是该蛋白抑制剂结核分枝杆菌的重组天冬酰胺酶的筛选中的用途，以及筛选方法选择所述抑制剂。本发明还涉及结核分枝杆菌的突变株。 展开▼

著录项

公开/公告号WO2014162102A1

专利类型

公开/公告日2014-10-09

原文格式PDF

申请/专利权人 UNIVERSITE PAUL SABATIER TOULOUSE III;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;
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申请/专利号WO2014FR50806

发明设计人 GOUZY ALEXANDRE;POQUET YANNICK;NEYROLLES OLIVIER;
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申请日2014-04-03

分类号C12N1/21;C12N9/82;C07K16/40;C12Q1/34;C12N15/11;A61P31/06;A61K39/04;

国家 WO

入库时间 2022-08-21 15:46:42

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