A method for determining endogenous and exogenous markers in blood

摘要

The method of the invention comprises preparing for analysis of a solution which contains substances, blood plasma, plus those substances which were present in whole blood within an adsorbed layer (were adsorbed) on blood cell surface. The method of the invention characterized in that substances which facilitate the transfer of the substances adsorbed on blood cell surface into the plasma are added to the whole (initial) blood sample. In accordance with the most preferred embodiment, a sodium chloride hypertonic solution or a certain amount of a dry salt powder of sodium chloride is added.;The method of the invention is intended for the analysis of all of the currently detectable endogenous substances and exogenous substances in blood but, in the first turn, for conducting pharmacological studies as well as for detecting tumor markers, immunomarkers, and doping control markers, which are transported in blood mostly on the blood cell surface.