首页> 外国专利> LECITHIN:CHOLESTEROL ACYLTRANSFERASE (LCAT) AND ITS ROLE IN NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)

LECITHIN:CHOLESTEROL ACYLTRANSFERASE (LCAT) AND ITS ROLE IN NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)

机译:卵磷脂:胆固醇酰基转移酶(LCAT)及其在壬酸脂肪肝疾病(NAFLD)中的作用

摘要

Lecithin:cholesterol acyltransferase (LCAT) is responsible for the esterification of the free cholesterol of plasma lipoproteins. In the present invention, we describe the role of LCAT in hepatic triglyceride accumulation and the development of diet-induced nonalcoholic fatty liver disease (NAFLD). LCAT is described as a novel therapeutic agent for the treatment of NAFLD.
机译:卵磷脂:胆固醇酰基转移酶(LCAT)负责血浆脂蛋白游离胆固醇的酯化。在本发明中,我们描述了LCAT在肝甘油三酸酯积累和饮食诱导的非酒精性脂肪肝疾病(NAFLD)的发展中的作用。 LCAT被描述为用于治疗NAFLD的新型治疗剂。

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