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LECITHIN:CHOLESTEROL ACYLTRANSFERASE (LCAT) AND ITS ROLE IN NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)
LECITHIN:CHOLESTEROL ACYLTRANSFERASE (LCAT) AND ITS ROLE IN NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)
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机译:卵磷脂:胆固醇酰基转移酶(LCAT)及其在壬酸脂肪肝疾病(NAFLD)中的作用
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摘要
Lecithin:cholesterol acyltransferase (LCAT) is responsible for the esterification of the free cholesterol of plasma lipoproteins. In the present invention, we describe the role of LCAT in hepatic triglyceride accumulation and the development of diet-induced nonalcoholic fatty liver disease (NAFLD). LCAT is described as a novel therapeutic agent for the treatment of NAFLD.
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