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MITOCHONDRIA-TARGETED ANTIOXIDANTS FOR TREATMENT OF AGE-RELATED BRAIN DISORDERS

机译:线粒体靶向抗氧化剂治疗年龄相关性脑疾病

摘要

A method for providing to a mammal a neuroprotective effect against a brain pathology that is associated with reactive oxygen species originating from mitochondria (mROS). The method includes the step of administering to the mammal an SkQ mitochondria-targeted antioxidant in an amount effective to provide said neuroprotective effect. The SkQ mitochondria-targeted antioxidant may be administered either prophylactically or for treatment with respect to brain pathologies other than brain trauma or stroke, and may be administered for treatment of brain trauma or stroke.
机译:一种向哺乳动物提供针对与来自线粒体(mROS)的活性氧相关的脑部病理的神经保护作用的方法。该方法包括以有效提供所述神经保护作用的量向哺乳动物施用靶向SkQ线粒体的抗氧化剂的步骤。可以预防性或针对除脑外伤或中风以外的脑病进行治疗,以SkQ线粒体为靶标的抗氧化剂进行给药,也可以对脑外伤或中风进行治疗。

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