首页> 外国专利> MATRIX PLATFORM FOR CULTURING STEM CELL INCLUDING HEPARIN-BASED HYDROGEL AND METHOD FOR PREPARING THE SAME

MATRIX PLATFORM FOR CULTURING STEM CELL INCLUDING HEPARIN-BASED HYDROGEL AND METHOD FOR PREPARING THE SAME

机译:培养包含肝素基水凝胶的干细胞的基质平台及其制备方法

摘要

The present invention relates to a matrix platform for culturing stem cells containing heparin-based hydrogel, especially, the matrix platform for culturing adult stem cells and a production method of the same. More specifically, the present invention relates to the matrix platform for culturing the stem cells which contains heparin and water soluble polymers, in which the content of the heparin is 1-40 wt% of the total weight of the culturing matrix platform. The matrix platform for culturing the stem cells is capable of supplying optimized environment for the adhesion and breeding of the stem cells, and maintains the pluripotency of the cultured stem cells to be effectively used in breeding and studying of the stem cells. [Reference numerals] (AA) Tissue culture flat;(BB) Heparin hydrogel (53 wt%);(CC) Heparin hydrogel (10 wt%);(DD) Heparin hydrogel+Type I collagen;(EE) Heparin hydrogel+fibronectin;(FF) PEG hydrogel;(GG) Alginate hydrogel
机译:本发明涉及用于培养含有肝素基水凝胶的干细胞的基质平台,特别是用于培养成体干细胞的基质平台及其生产方法。更具体地,本发明涉及用于培养含有肝素和水溶性聚合物的干细胞的基质平台,其中肝素的含量为培养基质平台的总重量的1-40wt%。用于培养干细胞的基质平台能够为干细胞的粘附和繁殖提供优化的环境,并保持培养的干细胞的多能性,以有效地用于干细胞的繁殖和研究。 [附图标记](AA)组织培养平板;(BB)肝素水凝胶(53 wt%);(CC)肝素水凝胶(10 wt%);(DD)肝素水凝胶+ I型胶原蛋白;(EE)肝素水凝胶+纤连蛋白;(FF)PEG水凝胶;(GG)海藻酸盐水凝胶

著录项

  • 公开/公告号KR20130133461A

    专利类型

  • 公开/公告日2013-12-09

    原文格式PDF

  • 申请/专利权人 GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY;

    申请/专利号KR20120056725

  • 发明设计人 TAE GI YOONG;KIM MI HYE;

    申请日2012-05-29

  • 分类号C12M3;C12N5/02;C12N5/074;

  • 国家 KR

  • 入库时间 2022-08-21 15:44:48

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