USE OF HMGB1 AS A BIOLOGICAL MARKER OF BOWEL INFLAMMATORY CONDITIONS, NON-INVASIVE METHOD FOR ITS DETECTION IN FECAL SAMPLES AND KIT THEREOF

摘要

The invention western blotting (Western blot) analysis or an appropriate antigen- represented by an ELISA assay using an antibody comprising the analysis of protocols for detecting the presence of HMGB1, HMGB1 in the presence of feces extracts, and chronic inflammatory bowel disease , especially Crohn's disease (CD) and the involvement of the protein in the pathogenesis of ulcerative colitis (UC) ( pathogenesis ) the via provides a noninvasive seupbeop (noninvasive method) for measuring the human intestinal inflammatory condition . The invention also includes a colorimetric kit for carrying out this method . ;