PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETIC COMPLICATIONS WHICH INCLUDES EXTRACT OF CAPSOSIPHON FULVESCENS OR COMPOUNDS ISOLATED THEREFROM AS ACTIVE INGREDIENTS

摘要

The present invention relates to novel uses of capsosiphon fulvescens extract or compounds isolated therefrom for preventing or treating diabetic complications and, more specifically, to a pharmaceutical composition and a health supplement for preventing or treating diabetic complications which include capsosiphon fulvescens extract, soluble extract of non-polar solvent, or compounds isolated therefrom (capsofulvesin A, capsofulvesin B, chalinasterol) as active ingredients. The capsosiphon fulvescens extracts or compounds isolated therefrom (capsofulvesin A, capsofulvesin B, chalinasterol) have excellent suppression activities on aldose reductase and excellent suppression activities on final glycation products. Therefore, the capsosiphon fulvescens extracts or compounds isolated therefrom can be utilized as medicines such as pharmaceutical compositions and health supplements for preventing or treating diabetic complications so that the value of the capsosiphon fulvescens extracts or compounds isolated therefrom can be extremely high when applying in food and medical industries. Specially, the capsosiphon fulvescens extracts or compounds isolated therefrom in the present invention are substances derived from natural substances and have stability without cytotoxicity so that the compositions of the present invention which includes the same as active ingredients can be safely used for long time.;COPYRIGHT KIPO 2014