HOST CELL WITH ADJUSTED GLYCEROL METABOLISM AND METHOD FOR MANUFACTURING GLYCEROL DEHYDRATASE METABOLITE USING SAME

摘要

The present invention relates to a microorganism with adjusted glycerol metabolism, a method for manufacturing a glycerol dehydratase metabolite from glycerol using the same, and a method for manufacturing the microorganism, and more particularly, to a microorganism for inactivating a glycerol-3-phosphate regulon repressor gene (glpR) on a chromosome and for manufacturing a glycerol dehydratase metabolite from glycerol, a method for manufacturing a glycerol dehydratase metabolite such as 3-hydroxypropionic acid and/or 1,3-propanediol and the like using the same, and a method for manufacturing the microorganism. The microorganism with adjusted glycerol metabolism according to the present invention has the effects of noticeably increasing growth of the microorganism and production of the glycerol dehydratase metabolite using glycerol of low costs as a carbon source and an energy source, thereby, effectively producing a glycerol dehydratase metabolite such as 3-hydroxypropionic acid and/or 1,3-propanediol and the like using the same.;COPYRIGHT KIPO 2014