A GELATIN NANOFIBROUS WEB CONTAINING PHAEODACTYLUM TRICONUTUM EXTRACTS AND WOUND DRESSING USING THE SAME

摘要

In the present invention, gelatin is dissolved in trifluoroethyl alcohol (TFE) which is a spinning solvent without conventionally extracting eicosapentaenoic acid (EPA) from phaeodactylum triconutum; a solution in which the gelatin and phaeodactylum triconutum extract are mixed is prepared by adding the phaeodactylum triconutum to the spinning solvent in which the gelatin is dissolved; and gelatin nanofibers on which the EPA is loaded by electrospinning the spinning solvent is manufactured in order to mix functional materials of microalgae into nanofibers to be used as a wound dressing. The EPA is confirmed to be loaded on the manufactured gelatin nanofibers, and the manufactured EPA-gelatin nanofibers has antibacterial functions, low cytotoxicity, and enhanced cell adhesion and cellular proliferation so that the manufactured EPA-gelatin nanofibers can be used as the wound dressing.