COMPOSITION FOR INHIBITING CELLULAR SENESCENCE COMPRISING EXTRACTS OF INULA JAPONICA THUNBERG OR BRITANIN ISOLATED FROM THE SAME

摘要

The present invention relates to a pharmaceutical composition for inhibiting the aging of fibroblasts, containing, as an active ingredient, an Inula japonica thunberg extract, britanin isolated therefrom, or a mixture thereof, and provides a pharmaceutical composition induced by Adriamycin for inhibiting the aging of fibroblasts. As such, the composition of the present invention can be useful to treat diseases, such as age-related diseases including skin aging, rheumatoid arthritis, osteoarthritis, hepatitis, chronic skin tissue damage, arteriosclerosis, prostatic hyperplasia, and liver cancer, by inhibiting the cell aging process of human fibroblasts. Further, the composition of the present invention is expected to be used for the development of functional anti-aging food, a vessel anti-aging drug, and cosmetics, which can inhibit cell aging.