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SOLID-SUPPORTED PRECURSOR COMPOUNDS FOR SYNTHESIS OF 18F RADIOPHARMACEUTICLAS, PREPARATION METHOD AND APPLICATIONS THEROF
SOLID-SUPPORTED PRECURSOR COMPOUNDS FOR SYNTHESIS OF 18F RADIOPHARMACEUTICLAS, PREPARATION METHOD AND APPLICATIONS THEROF
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机译:固体支持的前体化合物合成18F放射性药物的合成,制备方法及其应用
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摘要
The present invention relates to a solid precursor in the form of an organic salt, the solid precursor having a solid support, a method for manufacturing same, and an application thereof. The solid precursor of the present invention enables omission of the [18F]fluoride refining process using additional cartridge, and the use of excessive phase-transfer catalyst, and can easily remove remaining substance after reaction through the solid support inside the precursor. The solid precursor of the present invention is very appropriate for an automated synthesis device as an all-in-one system that can carry out overall process of [18F]fluorosis reaction, when used by charging in a cartridge.
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