Therapeutic agents targeting PRX3 for stress disorder and method of screening thereof

摘要

The invention method of producing a reaction emollient stress sensitive, stress sensitizer emollient stress improved food or feed for containing a preparation method thereof, the screening method of the stress sensitizer emollients, stress prevention or treatment a pharmaceutical composition of the disorders, the preparation of method, or prevention of a stress disorder treatment, stress reduction, or an information providing method for the mitigation, or prevention or improvement of a food composition for stress disorders, stress and stress disorders or sensitizer diagnosis caused by chronic stress. According to the present invention, PRX3 or may be in the TRX2 gene inhibiting the deacetylation of histones develop drugs using the mechanism to inhibit the PRX3 or TRX2 gene expression decreased, the drug screening methods of the present invention are stress, in particular, chronic by the stress that the symptoms of depression that can be triggered or exacerbated, can prevent or treat degenerative brain disease. ;