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New fatty acids having physiological activity comprising antimicrobial activity, Marine microorganism producing the new fatty acids and producing method of the new fatty acids using the marine microorganism
New fatty acids having physiological activity comprising antimicrobial activity, Marine microorganism producing the new fatty acids and producing method of the new fatty acids using the marine microorganism
in the present invention is to be used as a therapeutic agent for hyperlipidemia, exhibit antimicrobial activity of the formula 1-4 service is a fatty acid compound, and provides a manufacturing method using the medium adapted to the accession number KCTC 11975BP marine microorganisms and salts deposited by 12 g / L to produce a fatty acid compound efficiently. Provided such a novel fatty acid compounds and methods for their preparation according to the invention exhibit a variety of physiologically active threat posed by antibiotic-resistant pathogens, commercial supply of new antimicrobial agents to face the emergence of limited efficacy and bio-terrorism in recent antifungal drug it may be possible. R & 1 & In Formula 1 R 1 = R 2 = H Lim. R & 2 & In Formula 2 R = H Lim. R & 3 & R in Formula 3 1 = R 2 = R 3 = H Lim. R & 4 & In Formula 4 R 1 = R 2 = H Lim. ;
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机译:在本发明中用作高脂血症的治疗剂,显示出具有化学式1-4的抗菌活性,是一种脂肪酸化合物,并提供了一种使用适于保藏号KCTC 11975BP的海洋微生物和盐的培养基的制备方法以12 g / L的量沉积,可有效生产脂肪酸化合物。提供了根据本发明的这样的新型脂肪酸化合物及其制备方法,其显示出由抗药性病原体构成的多种生理活性威胁,新的抗微生物剂的商业供应以面对近来抗真菌药的功效有限和生物恐怖主义的出现。药物可能是可能的。 R& 1>在公式1中,R 1 Sub> = R 2 Sub> = H Lim。 R& 2>在式2中,R = H Lim。 R& 3公式3中的R 1 Sub> = R 2 Sub> = R 3 Sub> = H Lim。 R& <4>在公式4中,R 1 Sub> = R 2 Sub> = H Lim。 ;
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