首页> 外国专利> Non-vascular drug-eluting stent membrane using electrospinning, and method for preparing the same

Non-vascular drug-eluting stent membrane using electrospinning, and method for preparing the same

机译:使用静电纺丝的无血管药物洗脱支架膜及其制备方法

摘要

The present invention relates to a drug release stent and a method for non-vascular membrane by Electrospinning. While the non-drug-eluting stent for vascular membrane in accordance with the present invention is covered with a metal roller and then mounted on a Teflon rod, and rotating the stent, or to insert a metal stent covered with a Teflon rod and Teflon or silicone tubing over the primary coating layer on a metal stent while the formation of the mounting them on the rollers to rotate, by electrospinning a drug coating solution containing a polyurethane and anti-cancer agents, in continuous homogeneous surface than the stent and the membrane prepared by the dipping method is constant and stable thickness control drug release drug shows a release effect, significantly inhibit the growth of tumors and significantly reduces the weight of the tumor. Thus, the drug release for non-blood vessel stent according to the invention the membrane may be useful in preventing the progression of stenosis is a narrowing or widening jugeona lumen due to the occurrence of tumors, such as cancer. ;
机译:本发明涉及药物释放支架和通过电纺丝制造非血管膜的方法。在将根据本发明的用于血管膜的非药物洗脱支架覆盖有金属辊之后,将其安装在特氟龙棒上并旋转该支架,或者插入覆盖有特氟龙棒和特氟龙的金属支架,或者通过将包含聚氨酯和抗癌药的药物涂层溶液静电纺丝,在金属支架上的主涂层上方形成硅胶管,同时将它们安装在滚筒上以使其旋转,从而形成比支架和制备的膜更连续的均匀表面通过浸涂法恒定而稳定的厚度控制药物释放,药物显示出释放效果,明显抑制肿瘤的生长,并显着减轻肿瘤的重量。因此,根据本发明的用于非血管支架的药物释放膜可用于防止狭窄的发展,所述狭窄是由于肿瘤例如癌症的发生而变窄或变大的子宫腔。 ;

著录项

  • 公开/公告号KR101370607B1

    专利类型

  • 公开/公告日2014-03-07

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110074719

  • 申请日2011-07-27

  • 分类号A61F2/82;A61L27/28;A61L27/54;A61L27/04;

  • 国家 KR

  • 入库时间 2022-08-21 15:41:23

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