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Extract Containing Luteolin­7­diglucuronide Derived from Lippia citriodora and Cosmetic Composition Containing the Same

机译:柠檬柚中含有木犀草素7二葡糖醛酸苷的提取物及其化妆品组合物

摘要

PURPOSE: A cosmetic composition is provided to contain high purity luteolin-7-diglucuronide isolated and purified from Lippia citriodora as an active ingredient, and have effects of antioxidant, whitening, anti-wrinkle, anti-inflammation, antibiotic, improvement of atopy, and UV protection. CONSTITUTION: A manufacturing method of Lippia citiodora extract containing luteolin-7-diglucuronide is comprises: a step of extracting luteolin-7-diglucuronide by adding a solvent to Lippia citriodora, and concentrating; a step of obtaining luteolin-7-diglucuronide fraction by adding more than two kinds of solvents selected from the group comprising of water, ethanol, methanol, butanol, ethyl acetate, ethyl ether, chloroform and hexane to the concentrated extract; a step of removing the organic solvents and manufacturing fraction concentration powder by secondary concentration; a step of removing pigment and chlorophyll using column after dissolving the fraction concentration powder in solvent; a step of recrystalizing the extract, in which the pigment and chlorophyll are removed, by precipitation under the controlled pressure and temperature; and a step of obtaining powder type luteolin-7-diglucuronide by spray drying or freeze drying the precipitated pellet. A functional cosmetic composition comprises Lippia citriodora extract containing the luteolin-7-diglucuronide as an active ingredient. [Reference numerals] (AA) Sample (Sample 5)
机译:用途:提供一种化妆品组合物,其中包含从柠檬柠檬果中分离和纯化的高纯度木犀草素-7-地葡萄糖醛酸作为有效成分,并具有抗氧化剂,美白,抗皱,抗炎,抗生素,改善特应性和防紫外线。组成:一种含有木犀草素7-地葡糖醛酸的柠檬皮小花提取物的制备方法,包括以下步骤:通过向柠檬皮草中添加溶剂来提取木犀草素-7-地葡糖醛酸并浓缩;通过向浓缩的提取物中添加选自水,乙醇,甲醇,丁醇,乙酸乙酯,乙醚,氯仿和己烷中的两种以上的溶剂来获得木犀草素-7-二葡糖醛酸苷级分的步骤;去除有机溶剂并通过二次浓缩制备级分浓缩粉的步骤;将级分浓缩粉末溶解在溶剂中后,用柱除去色素和叶绿素的步骤。通过在控制的压力和温度下沉淀,使其中除去了色素和叶绿素的提取物重结晶的步骤;通过喷雾干燥或冷冻干燥沉淀的颗粒获得粉末型木犀草素-7-二葡萄糖醛酸的步骤。一种功能性化妆品组合物,包括含有木犀草素-7-地葡糖醛酸作为活性成分的柠檬小Li(Lippia citriodora)提取物。 [附图标记](AA)样本(样本5)

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