Lipoic acid PEGylated peptide derivative, method for preparing the same, and cosmetic compostion comprising the same for whitening or improving wrinkle

摘要

The invention -PEG- lipoic acid peptide derivatives , their preparation and include them or for whitening wrinkle relates to a cosmetic composition . Lipoic acid and peptide derivatives of the present invention is not -PEG- little cytotoxic safety , tyrosinase inhibiting activity , melanin production inhibition therefore appears active , MMP-1 activity and to inhibit the biosynthesis of collagen is excellent promoting activity , whitening or anti-wrinkle can be very useful as an ingredient in a cosmetic composition . ;