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USE OF AN NMDA RECEPTOR ANTAGONIST FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY
USE OF AN NMDA RECEPTOR ANTAGONIST FOR THE TREATMENT OF TINNITUS INDUCED BY COCHLEAR EXCITOTOXICITY
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机译:使用NMDA受体拮抗剂治疗耳蜗兴奋性毒性引起的耳鸣。
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摘要
The invention relates to methods for the prevention and/or treatment of tinnitus induced by cochlear excitotoxicity. In these methods, a pharmaceutical composition comprising an NMDA receptor antagonist is administered to an individual in need of such treatment by appropriate devices and/or formulations for local administration to the inner ear. The tinnitus to be prevented and/or treated may be provoked by acoustic trauma, presbycusis, ischemia, anoxia, treatment with one or more ototoxic medications, sudden deafness, or other cochlear excito-toxic-inducing occurrence.
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