INTEGRATED IRON (III) COMPOUNDS FOR TREATMENT AND PREVENTION OF SYMPTOMS OF IRON DEFICIENCY AND IRON DEFICIENCY ANEMIA

摘要

1. A complex compound of iron (III) with β-ketoamides or its pharmaceutical acceptable salts for use as a medicine. The complex compound of iron (III), preferably according to claim 1, containing at least one ligand of the formula (I): where the arrows indicate a coordination bond with one or different iron atoms, R is selected from the group consisting of optionally substituted alkyl and optionally substituted alkoxycarbonyl, R is selected from the group consisting of a hydrogen atom, an optionally substituted alkyl, a halogen atom and a cyano group, or R and R, together with the carbon atoms to which they are attached, form an optionally substituted 5- or 6-membered ring, which is optional may contain one or more heteroatoms, R and R are identical or different, and are respectively selected from the group consisting of a hydrogen atom, an optionally substituted amino group and an optionally substituted alkyl, or R and R, together with the nitrogen atom to which they are attached, form an optionally substituted 3-6 -membered ring, which optionally may contain one or more additional heteroatoms, or R and R together form a saturated or unsaturated, optionally substituted 5- or 6-membered ring, forming a ligand of the formula (Ia): where R and R correspond by the above definitions, either R and R together form a saturated or unsaturated, optionally substituted 5- or 6-membered ring, and R and R together form a saturated or unsaturated, optionally substituted 5- or 6-membered ring, forming a ligand of the formula (Ib): where R corresponds to this above definition, or pharmaceutically acceptable salts thereof. 3. The complex compound of iron (III) according to claim 2, containing at least m