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SYSTEM intravenous 'rubidium chloride, 82Rb, from the generator'

机译:SYSTEM静脉注射“来自发生器的氯化rub82Rb”

摘要

System for intravenous administration "rubidium chloride, 82 Rb, from the generator" refers to medicine, namely to the means for intravenous administration of radiopharmaceuticals (RFP) from the generator, and can be used in the diagnosis of myocardial perfusion and cancer by positron emission tomography. The system includes a generator (18) with an inlet (8) and the outlet (10) FITTINGS, the control unit (19), an injection pump (1), a container with eluent (2), four three-way cock (3, 7, 9, 14), conduits (4, 17, 20), pressure switches (5) and radioactivity (11) sterilizing filters (6, 12), a unidirectional valve (13), the syringe (15) and intravenous infusion catheter (16). The generator has an inlet and an outlet, the first three-way valves connected to the reservoir with the eluent and the pump for the elution, the second is fixed to the outlet fittings of the generator is connected to a conduit for transporting the eluate and in the end it is a second sterilizing filter and the third three-way valve connected to a unidirectional valve, to the catheter for intravenous infusion and a syringe, wherein the sterilizing filters include integral air valves, a pressure sensor is installed between the first three-way valve and the first sterilizing filter, radioactivity sensor - a sterilizing filter before the second, the fourth three-way valve located at the inlet fittings of the generator, and a unidirectional valve - sterilizing filter between the second and third three-way stopcock. The system allows to measure the activity of the drug when administered directly to the patient, provides the introduction of the necessary dose in automatic mode, provides an assessment of the state of the generator column sorbent using a pressure sensor, it is characterized by simplicity of construction and is intended for the assembly directly to PET centers. The developed software eliminates the need for manual calculations of radioactivity at the calibration of the instrument.
机译:静脉给药系统“来自发生器的氯化rub, 82 Rb”是指药物,即来自发生器的静脉注射放射性药物(RFP)的手段,可用于诊断通过正电子发射断层扫描检查心肌灌注和癌症。该系统包括带有入口(8)和出口(10)配件的发生器(18),控制单元(19),注射泵(1),带有洗脱液的容器(2),四个三通旋塞( 3、7、9、14),导管(4、17、20),压力开关(5)和放射性(11)灭菌过滤器(6、12),单向阀(13),注射器(15)和静脉注射输液导管(16)。发生器具有入口和出口,第一个三通阀与洗脱液和用于洗脱的泵连接到储液罐,第二个三通阀固定到发生器的出口配件,与用于输送洗脱液的导管连接。最后是第二个灭菌过滤器和连接到单向阀的第三个三通阀,静脉输液导管和注射器,其中,灭菌过滤器包括内置空气阀,前三个之间装有压力传感器单向阀和第一灭菌过滤器,放射性传感器-位于发生器入口配件处的第二,第四三通阀之前的灭菌过滤器,以及第二和第三三通旋塞阀之间的单向阀-灭菌过滤器。该系统允许直接向患者给药时测量药物的活性,以自动模式提供必要剂量的引入,使用压力传感器提供对发生器色谱柱吸附剂状态的评估,其特点是操作简单结构,旨在直接组装到PET中心。开发的软件消除了在仪器校准时手动计算放射性的需要。

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