首页> 外国专利> METHOD FOR EVALUATING RISK OF DEVELOPING UNFAVOURABLE CARDIOVASCULAR STATES IN PATIENTS WITH MYOCARDIAL DISEASES UNDERGONE BYPASS SURGERY

METHOD FOR EVALUATING RISK OF DEVELOPING UNFAVOURABLE CARDIOVASCULAR STATES IN PATIENTS WITH MYOCARDIAL DISEASES UNDERGONE BYPASS SURGERY

机译:评估伴有旁路手术的心肌病患者发展不良心血管状态的风险的方法

摘要

FIELD: medicine.;SUBSTANCE: method involves preparing a patient's blood serum sample by drying blood serum, milling the dry deposition and suspending in Vaseline oil. The prepared blood serum sample is analysed by IR-spectroscopy in the spectral range of 1200-1000 cm-1. That is ensured by determining a peak height of absorption bands with maxima 1165, 1050, 1025, 1005 cm-1. Then, the following relations are calculated: the relation of the peak height with maximum 1005 cm-1 to the peak height with maximum 1050 cm-1, and the relation of the peak height with maximum 1025 cm-1 to the peak height with maximum 1165 cm-1. The derived peak heights are compared to the normal peak heights (for healthy individuals) that make: 0.55±0.15 for the relation of the peak height with maximum 1005 cm-1 to the peak height with maximum 1050 cm-1, 1.44±0.59 for the relation of the peak height with maximum 1025 cm-1 to the peak height with maximum 1165 cm-1. If at least one of the derived relations of the peak heights lies outside the normal range, the patient suffering a myocardial disease and undergone a bypass surgery is referred to a high-risk category of the unfavourable cardiovascular states.;EFFECT: method enables the reliable and simple evaluation of the risk of the developing unfavourable cardiovascular states in the patients suffering myocardial diseases and undergone a bypass surgery.;4 ex
机译:领域:药物;方法:该方法涉及通过干燥血清,研磨干燥的沉积物并悬浮在凡士林油中来制备患者的血清样品。用红外光谱法在1200-1000 cm -1 光谱范围内对制备的血清样品进行分析。通过确定最大值为1165、1050、1025、1005 cm -1 的吸收带的峰高可以确保这一点。然后,计算出以下关系:最大高度为1005 cm -1 的峰高与最大1050 cm -1 的峰高的关系,以及最大峰值高度为1025 cm -1 ,最大峰值高度为1165 cm -1 。将得出的峰高与正常峰高(对于健康个体)进行比较,得出正常高度为0.55±0.15,最大1005 cm -1 的峰高与最大1050 cm的峰高的关系 -1 ,最大峰高1025 cm -1 与最大峰高1165 cm -1 的关系为1.44±0.59 。如果至少一个推导的峰高关系在正常范围之外,则患有心肌疾病且接受了搭桥手术的患者被称为心血管状况不利的高风险类别。并简单评估患有心肌疾病并接受了搭桥手术的患者发生不利的心血管状态的风险。4ex

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