QUINAZOLINE DERIVATIVES, POSSESSING ANTIDEPRESSANT, ANXIOLYTIC AND NOOTROPIC ACTIVITY

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to novel medication possessing antidepressant, anxiolytic and nootropic activity, which represents compound of general formula where: X is NH or 1,4-piperasino; R¹=H or CH₃; R²=H, OCH₃ or N(CH₃)₂.;EFFECT: on experimental models in vivo compounds, possessing original spectrum of psychotropic action, exceed medications of different pharmacological groups - aphobazolum, melipramin, phenotropil, diazepam in complex of useful qualities, and can be applied in treatment of patients with anxiety and depressive disorders.;4 tbl, 8 ex