METHOD FOR PHARMACOLOGICAL STIMULATION OF PEDICLE SKIN FLAP SURVIVAL WITH NICORANDYL

摘要

FIELD: medicine.;SUBSTANCE: pedicle skin flap survival is corrected in laboratory animals is corrected by modelling a flap on the second experimental day. On the first and fourth day of the experiment, nicorandyl is introduced intraperitoneally in a daily dose of 1.3 mg/kg in two stages.;EFFECT: higher skin flap survival in the reduced blood circulation environment ensured by opening the ATP-dependent potassium channels and providing the nitrate-like effect of nicorandyl in the specific experimental environment.;1 ex, 1 tbl