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METHOD FOR SIMULATING DELAYED HYPERRESPONSIVENESS TO MYCOBACTERIA BOVIS IN GUINEA PIGS

机译：豚鼠对牛分枝杆菌迟发型超敏反应的模拟方法

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摘要

FIELD: medicine.;SUBSTANCE: what is presented is a method for simulating a delayed hyperresponsiveness to mycobacteria bovis. Avirulent mycobacteria bovis of the strain BCG are administered intracutaneously to albino guinea pigs produced by consanguineous mating of brother x sister (F2); that is followed by forming a group (groups) of animals showing various extents of an inflammatory response in reaction to the intracutaneous administration of mycobacteria bovis of the strain BCG 30-35 days later.;EFFECT: method is effective in studying the mechanisms of the delayed hyperresponsiveness and assessing the efficacy of antituberculosis agents.;2 tbl, 5 ex

机译：领域：药物;物质：提出了一种模拟对牛分枝杆菌的迟发型高反应性的方法。将BCG毒株的无毒牛分枝杆菌皮内施用给由兄弟x姐妹近亲交配（F2）产生的白化豚鼠;然后在30-35天后，对BCG菌株的牛分枝杆菌皮内注射后，形成一组显示不同程度的炎症反应的动物。延缓高反应性并评估抗结核药的疗效。; 2 tbl，5 ex

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公开/公告号RU2517218C1

专利类型
公开/公告日2014-05-27

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIJA KURSKAJA GOSUDARSTVENNAJA SELSKOKHOZJAJSTVENNAJA AKADEMIJA IMENI PROFESSORA I.I. IVANOVA MINISTERSTVA SELSKOGO KHOZJAJSTVA ROSSIJSKOJ FEDERATSII;
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申请/专利号RU20120145515
发明设计人 MJASOEDOV JURIJ MIKHAJLOVICH;MOROZOV SERGEJ VLADIMIROVICH;
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申请日2012-10-25
分类号A61K39/04;A61P37/02;
国家 RU
入库时间 2022-08-21 15:38:33

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