METHODS, DEVICES AND SETS FOR DETECTION OR MONITORING OF ACUTE KIDNEY INJURY

摘要

FIELD: medicine.;SUBSTANCE: group of inventions relates to medicine and deals with a method of determining in an individual's sample of a protein of neutrophilic origin, gelatinase-associated lipocalin (NGAL), for determination of acute kidney injury in the individual, where the predominating amount of monomer and/or heterodimer forms of NGAL protein, in comparison with the dimer form of NGAL protein, shows that NGAL protein originates from the individual's kidneys and that the individual has acute kidney injury, whereas equal or predominating amount of the dimer form of NGAL protein, in comparison with the monomer or heterodimer form of NGAL protein shows that NGAL protein originates from the individual's neutrophils and that the said individual does not have acute kidney injury; a set for determination of relative amounts of monomer, dimer or heterodimer forms of NGAL; application of the device in the said method.;EFFECT: group of inventions ensures more accurate diagnosis and therefore contributes to better directed treatment.;17 cl, 2 ex, 10 dwg, 1 tbl