METHOD FOR PREDICTION OF DEVELOPING MALIGNANT GROWTHS IN RADIATION EXPOSURE

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine and is applicable for predicting developing malignant new growths in individuals under the conditions of the chronic low-intensity radiation exposure. What is performed is genetic typing of biological media of the body with real-time PCR with saliva used as a PCR matrix. If observing a combination of the genetic types XRCC1 280(GG) hOGG1 326(CC/CG) XPD1 751(AA) GSTM1(-) NOS3 774(TT/CT), a high risk of developing malignant new growths is predicted. If observing any of the major genetic types XRCC1 280GA, XPD1 751AC, hOGG1 326CG, CYP2C19 681GA and NOS3 VNTR, a low risk of developing malignant new growths is predicted.;EFFECT: invention enables the 2-hour testing procedure even in transportation conditions, and may be used in personnel screening in industries related to long-term contact to ionising radiation sources.;4 tbl, 1 ex