STRAIN OF INFLUENZA VIRUS OF SUBTYPE A/pochard/Siberia/249/08-MA H10N7 FOR OBTAINING ANTIGEN-CONTAINING DIAGNOSTIC PREPARATION AND DIAGNOSTIC POLYCLONAL SERUM, APPLICATION AS CONTROL REFERENCE-SAMPLE IN EVALUATING SPECIFICITY OF TEST SYSTEMS BASED ON PCR AND FOR STUDY OF ANTIVIRAL PREPARATIONS in vitro AND in vivo

摘要

FIELD: biotechnology.;SUBSTANCE: characterised strain of influenza virus of subtype A/pochard/Siberia/249/08-MA H10N7 is isolated from cloacal elution of pochard and adapted to mice line BALB/c. The strain is deposited in the Collection of viral infections and rickettsioses of Federal budget institution of science "State Research Centre of Virology and Biotechnology "Vector" (under the registration number V-592). The strain has the high antigenic affinity for modern variants of influenza virus of subtype H10 and suitable for production of polyclonal serum for determining belonging of influenza virus to subtype H10, and can also be used as a control reference sample in assessment of specificity of the test systems based on PCR, it has lethality for mice.;EFFECT: possibility to use the strain for the study of antiviral preparations in vivo.;5 tbl, 3 ex