OCTREOTIDE-CONTAINING COMPOSITION WITH DELAYED RELEASE WITH STABLY HIGH LEVEL OF IMPACT

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: group of inventions relates to field of pharmaceutics and medicine and deals with pharmaceutical composition with delayed release, which contains as active ingredient octreotide or its pharmaceutically acceptable salt and two different linear copolymers of polylactide and glycolide (LCPG), characterised by molar ratios lactide/glycolide 75:25 and different values of viscosity, for prolonged supportive treatment of patients with acromegaly and for treatment of severe forms of diarrhoea and hyperaemia, associated with malignant carcinoid tumours and tumours, cells of which produce vasoactive intestinal peptide.;EFFECT: group of inventions ensure stably high level and fast achievement of required level of impact of active substance.;10 cl, 5 ex, 3 tbl, 1 dwg