METHOD FOR DETERMINING RELATION OF BLOOD FLOWS IN PAIRED ORGANS OR PAIRED REGIONS OF INTEREST

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to functional diagnostics, and can be used in assessing the blood microcirculation status in a patient's limbs by determining a relation between the blood flows in the paired organs or paired regions of interest by radionuclide diagnostics. That is ensured by inserting a microcatheter with a two-way cock and two syringes attached, into the ulnar or other forearm vein. One syringe contains an indicator, an amount of which shall not exceed 0.3-0.5 ml, while the other syringe contains normal saline. Immediately after the indicator is introduced into the catheter, it is pushed on by normal saline from the second syringe. A camera is used to record gamma emission and a radioactivity-time curve is constructed. The radioactivity-time curves are rated by an area of the specified regions of interest y1(t)/S₁, y2(t)/S₂ to construct the initial radioactivity-time curves y1(t), y2(t), which are approximated by orthogonal polynominals α1(t), α2(t) in the form of a parametric curve ψ[α1(t), α2(t)], whereon a straight-line segment is specified between the points t₁ and t₂ for the following approximation implemented by the least square method and represented by the straight line y=kx+b. Herewith, y is an approximated radioactivity in the 1^st region of interest , x is an approximated radioactivity in the 2^nd region of interest, k=tgα, wherein α is an inclination of the straight line to an absciss, b is a segment of the y axis from the coordinate origin to a crossing point of the straight line and the y axis. The required relation D is defined as wherein Q₁ is the blood flow (ml/min) in the 1^st region of interest, Q₂ is the blood flow (ml/min) in the 2^nd region of interest.;EFFECT: method provides the timely and accurate diagnosis of limb pathology by determining the blood flow in the region of interest with respect to the examined limb in relation to this value in the contralateral limb.;2 cl, 5 dwg, 1 ex