multichannel fastscan of chromatographic peaks by means of a tandem mass spectrometer

摘要

A method for analyzing of two or more compound ions (105; a, b, c), which is composed of co-eluting precursor compounds, during a cycle analysis of a tandem mass spectrometer-system (100), said method comprising the steps of:Analyzing the compound ions (105; a, b, c) during a plurality of sets of subcycles comprises, wherein each compound ion (105; a, b, c) during each of the sets of subcycles comprises is analysed, whereby the subcycles comprises a set in a timed sequence take place, and wherein each sub-cycle a fixed collision cell energy (ce₁(A), ce₁(B), ce₁(C)) is used, wherein a plurality of compound ions in the subcycles comprises a set one after the other and be analyzed separately from one another, and wherein:a first compound ion (105; a, b, c) during a sub-cycle a first set of subcycles comprises using a first collision cell energy (ce₁(A), ce₁(B), ce₁(C)) is analysed; andthe first compound ion (105; a, b, c) during a sub-cycle a second set of subcycles comprises using a second collision cell energy (ce₁(A), ce₁(B), ce₁(C)), which extends from the first collision cell energy (ce₁(A), ce₁(B), ce₁(C)), is analyzed.