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SELF-EMULSIFYING COMPOSITIONS OF OMEGA3-FATTY ACIDS

机译:OMEGA3-脂肪酸的自乳化成分

摘要

PROBLEM TO BE SOLVED: To provide self-emulsifying compositions excellent in at least one of the self-emulsification, dispersibility, emulsion stability and absorbability, with no or low ethanol addition.SOLUTION: Provided is a self-emulsifying composition comprising at least one compound selected from the group consisting of 3-polyunsaturated fatty acids, pharmaceutically acceptable salts and esters thereof in a range of 50-95 mass% in total, and an emulsifier of which hydrophilic-lipophilic balance is 10 or higher in a range of 5-50 mass%, where the composition contains ethanol not more than 4 mass% of the total mass of the compound and the emulsifier.
机译:解决的问题:提供在不添加或低添加乙醇的情况下在自乳化,分散性,乳液稳定性和吸收性中的至少一种方面优异的自乳化组合物。解决方案:提供一种包含至少一种化合物的自乳化组合物。选自由以下组成的组:3-多不饱和脂肪酸,其药学上可接受的盐和酯,其总量在50-95质量%的范围内,并且其亲水-亲脂性平衡为10或更高且在5-50的范围内的乳化剂质量%,其中组合物包含的乙醇不超过化合物和乳化剂总质量的4质量%。

著录项

  • 公开/公告号JP2015187177A

    专利类型

  • 公开/公告日2015-10-29

    原文格式PDF

  • 申请/专利权人 MOCHIDA PHARMACEUT CO LTD;

    申请/专利号JP20150143879

  • 发明设计人 FUJII HIROTATSU;YAMAGATA MOTOO;

    申请日2015-07-21

  • 分类号A61K31/202;A61K31/232;A61K47/34;A61K47/26;A61K47/24;A61K47/10;A61P3/06;A61P7/02;A61P9/10;A61P9;A61P25;A61P35;A61P29;A61P3;A61K9/107;

  • 国家 JP

  • 入库时间 2022-08-21 15:35:08

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