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EVALUATION INDEX FOR CULTIVATION PRODUCT OF STEM CELL AND USE OF THE SAME

机译:干细胞培养产物的评价指标及其用途

摘要

PROBLEM TO BE SOLVED: To provide an index useful for evaluation of the culture supernatant of a stem cell and the use of it.SOLUTION: As a method for evaluating the culture supernatant of a stem cell, a measuring process is executed for measuring one type or two or more types of elements selected from a group made up of the following elements of the culture supernatant of the stem cell: a first element which is protein having monocyte chemotactic promoting factor-1 (MCP-1) activity; a second element which is protein having out-of-cell domain activity of sialic acid coupling immunoglobulin lectin-9; and a third element which is at least one type of chondroitin sulfuric acid and chondroitin sulfuric acid proteoglycan. Measuring such elements enables evaluation of usability of the stem cell culture supernatant for therapeutic use.
机译:解决的问题:为了提供用于评估干细胞的培养上清液及其使用的指标。​​解决方案:作为评估干细胞的培养上清液的方法,执行测量过程以测量一种类型或选自由干细胞的培养上清液的以下元素组成的组中的两种或更多种元素:第一元素是具有单核细胞趋化促进因子-1(MCP-1)活性的蛋白质;第二种成分是具有唾液酸偶联免疫球蛋白凝集素9的细胞外结构域活性的蛋白质;第三元素是软骨素硫酸和软骨素硫酸蛋白聚糖中的至少一种。测量这样的元素使得能够评估干细胞培养上清液用于治疗用途的可用性。

著录项

  • 公开/公告号JP2015166694A

    专利类型

  • 公开/公告日2015-09-24

    原文格式PDF

  • 申请/专利权人 NAGOYA UNIV;

    申请/专利号JP20140040952

  • 发明设计人 YAMAMOTO AKIHITO;MATSUBARA KOKI;

    申请日2014-03-03

  • 分类号G01N33/53;A61K35/32;A61K38;A61P29;A61P3/10;A61K31/726;G01N33/15;G01N33/50;C12N5/10;C12Q1/02;C12N15/09;

  • 国家 JP

  • 入库时间 2022-08-21 15:34:58

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