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ANTI-CANINE N-TERMINAL PRO-ATRIAL NATRIURETIC PEPTIDE ANTIBODY AND IMMUNOLOGICAL MEASUREMENT METHOD USING THE SAME, AND KIT FOR IMMUNOLOGICAL MEASUREMENT
ANTI-CANINE N-TERMINAL PRO-ATRIAL NATRIURETIC PEPTIDE ANTIBODY AND IMMUNOLOGICAL MEASUREMENT METHOD USING THE SAME, AND KIT FOR IMMUNOLOGICAL MEASUREMENT
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机译:抗犬N末端原发性钠尿肽抗体及其免疫学测定方法及用该试剂盒进行免疫学测定
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摘要
PROBLEM TO BE SOLVED: To provide an anti-canine N-terminal pro-atrial natriuretic peptide antibody (Anti-canine NT-proANP antibody), an immunological measurement method for measuring canine N-terminal pro-atrial natriuretic peptide using this antibody (canine NT-proANP), and a method for detecting heart disease or a parasitic infection of the heart in a companion animal.;SOLUTION: An anti-canine N-terminal pro-atrial natriuretic peptide antibody of this invention consists of a different amino acid sequence portion from an amino acid sequence of human NT-proANP, for example, anti-canine NT-proANP (31-67) antibody recognizing a partial portion or a whole portion of the amino acid sequence 31 to 67 of canine NT-proANP, or anti-canine NT-proANP (68-98) antibody recognizing a partial portion or a whole portion of the amino acid sequence 68 to 98 of the canine NT-proANP. The immunological measurement method of canine NT-proANP of this invention is based on a sandwich measurement method using one or two kinds of this antibody. And the invention can detect heart disease of companion animals such as a dog and a parasitic infection of the heart, for example mitral insufficiency, cardiac insufficiency, or canine filariasis.;COPYRIGHT: (C)2015,JPO&INPIT
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