hypoxia-inducible factor (HIF) active reporter cell line

摘要

the present invention, the construction of new hypoxia-inducible factor (HIF) responsive reporter gene construct, it about the genetic constructs and vectors containing. Furthermore, the invention relates to stable cell lines that contain HIF-responsive reporter construct, as well as for the identification of modulators of HIF activity, methods and uses of the inventive constructs and cell lines.