-DERIVATIVES OF CIS-UNSATURATED FATTY ACIDS INTENDED FOR USE AS DRUG

摘要

PROBLEM TO BE SOLVED: To provide a drug to be used in the prevention and/or treatment of diseases based on changes in the lipids of a cellular membrane such as, for example, changes in the level, composition or structure of these lipids.SOLUTION: The present invention provides an -derivative of cis-unsaturated fatty acid, comprising a compound of cis-COOR-XCH-(CH2)a-CH=CH-(CH2)b-CH3 or salt thereof, in the formula, (a) and (b) can take any value between 0 and 14, (X) is substituted with a group selected from OH, NH2, CH3, F, F3C, HS, O-CH3, PO4(CH2-CH3)2 and CH3COO, and (R) is substituted with a group selected from H, sodium (Na), methyl ester (OMe) and ethyl ester (EE) or ammonium (NH3).