deuterated ribonucleoside, N protection phosphoramidite, and the synthesis of oligonucleotides

摘要

The present invention is high purity deuterium sugar, deuterated phosphoramidite, deuterated nucleic acid base , deuterated nucleosides, deuterated oligonucleotides, and may indicate biochemically useful and biologically valuable properties and thus have potential for therapeutic use, the defined sequence of the heavy and it is directed to the synthesis of the hydrogenation RNA.BACKGROUND 9A-B