A system for identifying associations between genes associated with perturbation factors and hyperpigmentation of the skin

摘要

A system for identifying associations between genes associated with perturbation factors and skin hyperpigmentation using association maps. The system includes a computer readable medium having a plurality of stored instances and a gene expression signature associated with hyperpigmentation of the skin. Each instance includes an ordered instance list of identifiers for differentially expressed genes, and a gene expression signature associated with hyperpigmentation is a differentially expressed gene or benchmark associated with hyperpigmentation A gene expression signature list of identifiers representing differentially expressed genes associated with the whitening agent to be. The system evaluates gene expression signatures associated with hyperpigmentation and instances stored in a computer readable medium, compares gene expression signatures associated with hyperpigmentation with multiple instances, and / or multiple instances Also included is a programmable computer having computer readable instructions that cause each of them to be assigned a relevance score.