HUMAN PANCREATIC POLYPEPTIDE (HPP) ANALOGUES AND THEIR EFFECTS ON FEEDING BEHAVIOR

摘要

PROBLEM TO BE SOLVED: To provide uses of agents for controlling appetite, feeding, food intake, energy expenditure and calorie intake, particularly in the field of obesity.SOLUTION: The present invention provides: analogues of human pancreatic polypeptides which differ from native human pancreatic polypeptide in respect of amino acid substitutions at one or more residues; and also uses of one or more of the compounds, methods of using one or more of the compounds, compositions containing one or more of the compounds; and methods of making the compounds.