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ACID PUMP ANTAGONIST FOR THERAPY OF DISEASE INVOLVING ABNORMAL GASTROINTESTINAL MOTILITY

机译:酸泵拮抗剂治疗涉及异常胃肠道运动性疾病的疾病

摘要

PROBLEM TO BE SOLVED: To find an agent normalizing interdigestive motility of gastrointestinal tracts.SOLUTION: The present invention relates to use of a compound having acid pump antagonistic activity, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the same, for manufacturing a medicine for prevention or therapy of a disease involving abnormal gastrointestinal motility. In addition, the present invention relates to a preventive or therapeutic method of the disease, comprising administration of the compound or a pharmaceutical composition comprising the same to a human or animal. The compound, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the same may be used in combination with one or more second active agents. Further, the present invention relates to a pharmaceutical composition comprising a compound having acid pump antagonistic activity or a pharmaceutically acceptable acid thereof and a kit which are used in prevention or therapy of the disease.
机译:解决的问题:寻找使胃肠道的消化道蠕动正常化的药剂。解决方案:本发明涉及具有酸泵拮抗活性的化合物,其药学上可接受的盐或包含该化合物的药物组合物在制造中的用途。预防或治疗胃肠动力异常的药物。另外,本发明涉及该疾病的预防或治疗方法,包括将所述化合物或包含所述化合物的药物组合物施用于人或动物。该化合物,其药学上可接受的盐或包含该化合物的药物组合物可以与一种或多种第二活性剂组合使用。此外,本发明涉及用于预防或治疗疾病的包含具有酸泵拮抗活性的化合物或其药学上可接受的酸的药物组合物和试剂盒。

著录项

  • 公开/公告号JP2015038140A

    专利类型

  • 公开/公告日2015-02-26

    原文格式PDF

  • 申请/专利权人 RAQUALIA PHARMA INC;

    申请/专利号JP20140217434

  • 发明设计人 TAKAHASHI NOBUYUKI;KOIZUMI SHINICHI;

    申请日2014-10-24

  • 分类号A61K45;A61P43;A61P1;A61P1/14;A61K31/4184;A61K31/5377;A61K31/4439;A61K31/437;A61K31/4375;A61K31/506;A61K31/5025;A61K45/06;A61K31/65;A61K31/4164;A61K31/60;A61K33/24;A61K31/4188;

  • 国家 JP

  • 入库时间 2022-08-21 15:32:38

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