quantitative multi-spectral photoacoustic tomography of tissue biomarkers

摘要

I imaging to detect three-dimensionally and quantitatively [challenges] biomarkers. Multispectral photoacoustic tomography method for imaging a target tissue comprising biomarkers that target [SOLUTION] tissue, the target tissue with light emitting units to emit the pattern of the pulsed light irradiation of at least one in the light irradiation a plurality of wavelengths detected by the detector the pressure signal from the biomarkers irradiated with light, and the target tissue, in response to the light irradiation, the pressure signal is generated in the target tissue, Bio that target tissue in the target tissue and a step of reconstructing the tomographic images for quantitative distribution of the marker. Light illumination wavelength also depends on the inversion scheme providing scheme spectral processing of one, a tomographic image of at least the pressure signal is analyzed using a photon propagation model, the pressure signal is also dependent on the light irradiation fluence on the target tissue . [Selection] Figure Figure 1